Late Angiographic Stent Thrombosis (LAST) Events With Drug-Eluting Stents

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Late angiographic stent thrombosis (LAST) events with drug-eluting stents.

OBJECTIVES We sought to describe the incidence of late angiographic stent thrombosis (LAST) events in an unselected drug-eluting stent (DES) population. BACKGROUND Concerns have been raised that LAST may be a potential limitation of DES. METHODS We have previously reported the angiographic incidence of early stent thrombosis (1.0%) in this prospective cohort of 2,006 patients treated with e...

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Late and Very Late Stent Thrombosis in the Era of Second-generation Drug-eluting Stents

Stent thrombosis is a life-threatening complication of percutaneous coronary intervention that often results in ST-segment myocardial infarction or sudden cardiac death. First-generation drug-eluting stents (DESs) are associated with an increased risk of late and very late stent thrombosis compared with baremetal stents due to delayed endothelialisation of the stent struts. The second-generatio...

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Very late stent thrombosis with newer drug-eluting stents: no longer an issue?

The European Congress of Cardiology witnessed during only a 5-year time period the most opposite perceptions medical progress can engender, both excitement and disappointment. Drug-eluting stents (DES) were responsible for that. In Stockholm 2001 the first DES-trial (RAVEL: randomized study with the sirolimus-coated BX velocity balloon-expandable stent) yielded awesome results for sirolimus-elu...

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Late stent thrombosis after drug-eluting stent: seeing is understanding.

Following the inspiration of Dr S. Windecker, the team from Bern, Switzerland, has contributed 30 studies on drug-eluting stent efficacy and safety, several of which represent essential pieces in the puzzle. The article in this issue of Circulation by Cook et al1 belongs to that select group of key references. The series of robust and detailed reports on the Bern-Rotterdam cohort studies have c...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2005

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2005.02.086